Revelation of John 16:3

angel--So B and ANDREAS. But A, C, and Vulgate omit it. upon--Greek, "into." became as . . . blood--answering to another Egyptian plague. of a dead man--putrefying. living soul--So B and ANDREAS. But A, C, and Syriac, "soul of life" (compare Gen 1:30; Gen 7:21-22). in the sea--So B and ANDREAS. But A, C, and Syriac read, "(as respects) the things in the sea."

In this chapter we have an account of the pouring forth of these vials that were filled with the wrath of God. They were poured out upon the whole antichristian empire, and on every thing appertaining to it. I. Upon the earth (Rev 16:2). II. Upon the sea (Rev 16:3). III. Upon the rivers and fountains of water (Rev 16:4). Here the heavenly hosts proclaim and applaud the righteousness of the judgments of God. IV. The fourth vial was poured out on the sun (Rev 16:8). V. The fifth on the seat of the beast. VI. The sixth on the river Euphrates. VII. The seventh in the air, upon which the cities of the nations fell, and great Babylon came in remembrance before God.

16:3-4 The plagues of the second and third bowls are similar to the first plague of Egypt (Exod 7:17-21). Perhaps John had in mind that much of Rome’s food and wealth came by sea. After Julius Caesar rid the sea of pirates, shipping became Rome’s lifeblood. Its end would mean economic death for the empire (see Rev 18:17-19).