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door-- (Co2 2:12). An opening for the extension of the Gospel. Wise men are on the watch for, and avail themselves of, opportunities. So "door of hope," Hos 2:15. "Door of faith," Act 14:27. "An open door," Rev 3:8. "A door of utterance," Col 4:3. "Great," that is, extensive. "Effectual," that is, requiring great labors [ESTIUS]; or opportune for effecting great results [BEZA]. many adversaries--who would block up the way and prevent us from entering the open door. Not here false teachers, but open adversaries: both Jews and heathen. After Paul, by his now long-continued labors at Ephesus, had produced effects which threatened the interests of those whose gains were derived from idolatry, "many adversaries" arose (Act 19:9-23). Where great good is, there evil is sure to start up as its antagonist.

In this chapter the apostle, I. Gives directions about some charitable collection to be made in this church, for the afflicted and impoverished churches in Judea (Co1 16:1-4). II. He talks of paying them a visit (Co1 16:5-9). III. He recommends Timothy to them, and tells them Apollos intended to come to them (Co1 16:10-12). IV. He presses them to watchfulness, constancy, charity, and to pay a due regard to all who helped him and his fellow-labourers in their work (Co1 16:13-19). V. After salutations from others, and his own, he closes the epistle with a solemn admonition to them, and his good wishes for them (Co1 16:20 to the end).